Title:	Acute flaxseed intake reduces postprandial glycemia in subjects with type 2 diabetes : a randomized crossover clinical trial
Authors:	Moreira, Fernanda Duarte Reis, Caio Eduardo Gonçalves Welker, Alexis Fonseca Gallassi, Andrea Donatti
metadata.dc.identifier.orcid:	https://orcid.org/0000-0002-4923-9114 https://orcid.org/0000-0001-7260-9497 https://orcid.org/0000-0002-5894-005X https://orcid.org/0000-0003-1852-485X
metadata.dc.contributor.affiliation:	Ministério da Saúde, Coordenação Geral de Atenção às Pessoas com Doenças Crônicas Universidade de Brasília, Programa de Pós-Graduação em Ciências e Tecnologias em Saúde Universidade de Brasília, Departamento de Nutrição Universidade de Brasília, Programa de Pós-Graduação em Ciências e Tecnologias em Saúde Universidade de Brasília, Programa de Pós-Graduação em Ciências e Tecnologias em Saúde
Assunto::	Diabetes Glicemia Fibra alimentar Linhaça Carboidratos - nutrição humana
Issue Date:	10-Sep-2022
Publisher:	MDPI
Citation:	MOREIRA, Fernanda Duarte; REIS, Caio Eduardo Gonçalves; WELKER, Alexis Fonseca; GALLASSI, Andrea Donatti. Acute flaxseed intake reduces postprandial glycemia in subjects with type 2 diabetes: a randomized crossover clinical trial. Nutrients, [S.l], v. 14, n. 18, e3736, 2022. DOI:https://doi.org/10.3390/nu14183736. Disponível em: https://www.mdpi.com/2072-6643/14/18/3736. Acesso em: 19 ago 2025.
Abstract:	Background: Postprandial glycemic excursions are associated with impairment control of diabetes mellitus. Long-term consumption of flaxseed can lower blood glucose levels; however, its effects on the postprandial glycemic response remain unknown. Therefore, this study aimed to evaluate the acute effects of raw flaxseed consumption on the 2 h postprandial glycemic curve in men with type 2 diabetes mellitus (T2DM). Methods: This was a randomized crossover clinical trial. Nineteen men with T2DM were randomly assigned a standardized breakfast without (control) or with a previous intake of 15 g of ground raw golden flaxseed (flax). Glycemia was measured at fasting and postprandial at 15, 30, 45, 60, 90, and 120 min. Palatability markers (visual appeal, smell, and pleasantness of taste) and taste intensity (sweetness, saltiness, bitterness, sourness, and creaminess) were evaluated. Results: The peak glucose rise and the 2 h AUC glycemic response reduced in the flax group by 17% (p = 0.001) and 24% (p < 0.001), respectively. The glucose peak time, palatability, and taste parameters did not differ between the two groups. Conclusions: Ingestion of 15 g of ground raw golden flaxseed before breakfast decreases the 2 h postprandial glycemic response in men with T2DM.
metadata.dc.description.unidade:	Faculdade de Ciências e Tecnologias em Saúde (FCTS) – Campus UnB Ceilândia Faculdade de Ciências da Saúde (FS) Departamento de Nutrição (FS NUT)
metadata.dc.description.ppg:	Programa de Pós-Graduação em Ciências e Tecnologias em Saúde Programa de Pós-Graduação em Nutrição Humana
Licença::	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
DOI:	https://doi.org/10.3390/nu14183736
Appears in Collections:	Artigos publicados em periódicos e afins

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