Título:	Phenolic compound profile by UPLC-MS/MS and encapsulation with chitosan of Spondias mombin L. fruit peel extract from Cerrado hotspot-Brazil
Autor(es):	Brito, Giovanna Oliveira de Reis, Bruna Cabral Ferreira, Eduardo Antonio Junqueira, Nilton Tadeu Vilela Barreto, Lívia Cristina Lira de Sá Mattivi, Fulvio Vrhovsek, Urska Gris, Eliana Fortes
ORCID:	https://orcid.org/0000-0001-8868-9321 https://orcid.org/0000-0001-8197-4349 https://orcid.org/0000-0003-4935-5876 https://orcid.org/0000-0003-0083-4075
Afiliação do autor:	University of Brasilia, Faculty of Ceilandia, Graduate Program in Health Sciences and Technologies University of Brasilia, Faculty of Ceilandia, Graduate Program in Health Sciences and Technologies University of Brasilia, Faculty of Ceilandia Brazilian Agricultural Research Corporation, EMBRAPA Brazilian Agricultural Research Corporation, EMBRAPA University of Trento, Department of Cellular, Computational and Integrative Biology, CIBIO Edmund Mach Foundation Edmund Mach Foundation University of Brasilia, Faculty of Ceilandia, Graduate Program in Health Sciences and Technologies
Assunto:	Plantas - compostos bioativos Compostos fenólicos Cerrados - Brasil Quitosana Secagem por atomização Cajá
Data de publicação:	7-Abr-2022
Editora:	MDPI
Referência:	BRITO, Giovanna Oliveira de et al. Phenolic compound profile by UPLC-MS/MS and encapsulation with chitosan of Spondias mombin L. fruit peel extract from Cerrado hotspot-Brazil. Molecules, Basel, v. 27, n. 8, e2382, 2022. DOI: https://doi.org/10.3390/molecules27082382. Disponível em: https://www.mdpi.com/1420-3049/27/8/2382. Acesso em: 16 jul. 2025.
Abstract:	Taperebá (Spondias mombin L.) is a native species of the Brazilian Cerrado that has shown important characteristics such as a significant phenolic compound content and biological activities. The present study aimed to characterize the phenolic compound profile and antioxidant activity in taperebá peel extract, as well as microencapsulating the extract with chitosan and evaluating the stability of the microparticles. The evaluation of the profile of phenolic compounds was carried out by UPLC-MS/MS. The in vitro antioxidant activity was evaluated by DPPH and ABTS methods. The microparticles were obtained by spray drying and were submitted to a stability study under different temperatures. In general, the results showed a significant content of polyphenols and antioxidant activity. The results of UPLC-MS/MS demonstrated a significant content of polyphenols in taperebá peel, highlighting the high content of ellagic acid and quercetin compounds. There was significant retention of phenolic compounds when microencapsulated, demonstrating high retention at all evaluated temperatures. This study is the first to microencapsulate the extract of taperebá peel, in addition to identifying and quantifying some compounds in this fruit.
Unidade Acadêmica:	Faculdade de Ciências e Tecnologias em Saúde (FCTS) – Campus UnB Ceilândia
Programa de pós-graduação:	Programa de Pós-Graduação em Ciências e Tecnologias em Saúde
Licença:	(CC BY) Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
DOI:	https://doi.org/10.3390/molecules27082382
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