Manual and alternative therapies as non‑pharmacological interventions for pain and stress control in newborns : a systematic review

Shayani, Leva Arani; Marães, Vera Regina Fernandes da Silva

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Campo DC	Valor	Lengua/Idioma
dc.contributor.author	Shayani, Leva Arani	-
dc.contributor.author	Marães, Vera Regina Fernandes da Silva	-
dc.date.accessioned	2025-09-19T14:12:31Z	-
dc.date.available	2025-09-19T14:12:31Z	-
dc.date.issued	2022-09-13	-
dc.identifier.citation	SHAYANI, Leva A.; MARÃES, Vera Regina F. da S. Manual and alternative therapies as non‑pharmacological interventions for pain and stress control in newborns: a systematic review. World Journal of Pediatrics, [S.l.], v. 19, p. 35–47, 2023. DOI: https://doi.org/10.1007/s12519-022-00601-w. Disponível em: https://link.springer.com/article/10.1007/s12519-022-00601-w#rightslink. Acesso em: 11 jun. 2025.	pt_BR
dc.identifier.uri	http://repositorio.unb.br/handle/10482/52469	-
dc.language.iso	eng	pt_BR
dc.publisher	Springer Nature	pt_BR
dc.rights	Acesso Restrito	pt_BR
dc.title	Manual and alternative therapies as non‑pharmacological interventions for pain and stress control in newborns : a systematic review	pt_BR
dc.type	Artigo	pt_BR
dc.subject.keyword	Recém-nascidos - prematuros	pt_BR
dc.subject.keyword	Dor	pt_BR
dc.subject.keyword	Estresse	pt_BR
dc.subject.keyword	Terapias alternativas	pt_BR
dc.identifier.doi	https://doi.org/10.1007/s12519-022-00601-w	pt_BR
dc.relation.publisherversion	https://link.springer.com/article/10.1007/s12519-022-00601-w#rightslink	pt_BR
dc.description.abstract1	Background Supporting therapies that provide stress and pain control of preterm and term newborns infants contribute positively to the neuropsychomotor development. Non-pharmacological interventions that involve manual techniques are described, considering protocols that can be reproduced by physical therapists, with positive and negative outcomes reports. Data sources Systematic review follows PRISMA 2020 statements guidelines. Primary and specifc health sciences databases (Science Direct, Pubmed, Scielo, Embase and Scopus) were consulted between October 2021 and May 2022. Articles considered were clinical trials, randomized or not, that included descriptions of the type of intervention as non-pharmacological and that studied the following outcomes: “pain” and “stress”. Results Fifteen articles were selected for analysis, reaching a methodological quality of at least 3 on the Jadad Scale for the Quality of Researched Sources. The non-pharmacological therapies most applied in isolation were massage, swaddling or wrapping, gentle touch and kinesthetic stimulation, and the combined therapies were non-nutritive sucking and swaddling, oral sucrose and swaddling, sensory stimulation and familiar odors, and sensory saturation. The outcomes found were relaxation, pain, and stress reduction after the application of painful procedures. The behavioral changes included crying, grimacing, yawning, sneezing, jerky arm or leg movements, startles, and fnger faring. The vital signs included heart rate, blood oxygen saturation level, and pulse respiration. Conclusions Combined techniques lead to better results in controlling neonatal pain when compared to isolated techniques. They can be applied both in preterm and term infants in a safe way and are reproducible in any health unit in a simple and economical way.	pt_BR
dc.identifier.orcid	https://orcid.org/0000-0002-9104-7415	pt_BR
dc.identifier.orcid	https://orcid.org/0000-0001-6605-0308	pt_BR
dc.contributor.affiliation	Universidade de Brasília	pt_BR
dc.contributor.affiliation	Universidade de Brasília	pt_BR
dc.description.unidade	Faculdade de Ciências e Tecnologias em Saúde (FCTS) – Campus UnB Ceilândia	pt_BR
dc.description.ppg	Programa de Pós-Graduação em Ciências e Tecnologias em Saúde	pt_BR
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