Título:	Initial muscle quality affects individual responsiveness of interleukin-6 and creatine kinase following acute eccentric exercise in sedentary obese older women
Autor(es):	Sousa Neto, Ivo Vieira de Nascimento, Dahan da Cunha Prestes, Jonato Fonseca, Eduardo Fernandes da Celes, Rodrigo Souza Rolnick, Nicholas Barbalho, Yuri Gustavo de Sousa Silva, Alessandro de Oliveira Stival, Marina Morato Lima, Luciano Ramos de Funghetto, Silvana Schwerz
Assunto:	Citocinas Idosos - saúde e higiene Atividade física
Data de publicação:	31-Mar-2022
Editora:	MDPI
Referência:	SOUSA NETO, Ivo Vieira de et al. Initial muscle quality affects individual responsiveness of interleukin-6 and creatine kinase following acute eccentric exercise in sedentary obese older women. Biology, v. 11, n. 4, p. 1-16, 2022. DOI 10.3390/biology11040537. Disponível em: https://www.mdpi.com/2079-7737/11/4/537. Acesso em: 27 abr. 2022.
Abstract:	This study aimed to evaluate the time course and responsiveness of plasma interleukin-6 (IL-6) and creatine kinase (CK) levels following acute eccentric resistance exercise in sedentary obese older women with a different muscle quality index (MQI). Eighty-eight participants (69.4 ± 6.06 years) completed an acute eccentric resistance exercise (7 sets of 10 repetitions at 110% of 10-repetition maximum with 3 min rest interval). Participants were divided into two groups: high or low MQI according to 50th percentile cut-off. The responsiveness was based on minimal clinical important difference. There were no differences between groups and time on IL-6 and CK levels (p > 0.05). However, the high MQI group displayed a lower proportion of low responders (1 for laboratory and 2 for field-based vs. 5 and 4) and a higher proportion of high responders for IL-6 (7 for laboratory and 6 for field-based vs. 4 and 5) compared to low MQI group. In addition, the high MQI group showed a higher proportion of high responders for CK (11 for laboratory and 9 for field-based vs. 6 and 6) compared to low MQI. A prior MQI screening can provide feedback to understand the magnitude response. Individual responsiveness should be taken into consideration for maximizing eccentric exercise prescription.
Unidade Acadêmica:	Faculdade UnB Ceilândia (FCE) Curso de Enfermagem (FCE-ENF)
Licença:	Biology - Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). FONTE: https://www.mdpi.com/openaccess#Permissions. Acesso em: 27 abr. 2022.
DOI:	https:// doi.org/10.3390/biology11040537
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