Title:	Glycemic Index of gluten-free bread and their main ingredients : a systematic review and meta-analysis
Authors:	Romão, Bernardo Falcomer, Ana Luísa Palos, Gabriela Cavalcante, Sandra Botelho, Raquel Braz Assunção Nakano, Eduardo Yoshio Raposo, António Shakeel, Faiyaz Alshehri, Sultan Mahdi, Wael A. Zandonadi, Renata Puppin
metadata.dc.identifier.orcid:	https://orcid.org/0000-0003-2361-8906 https://orcid.org/0000-0002-0369-287X https://orcid.org/0000-0002-9071-8512 https://orcid.org/0000-0002-5286-2249 https://orcid.org/0000-0002-6109-0885 https://orcid.org/0000-0002-0922-9819 https://orcid.org/0000-0002-7083-1753 https://orcid.org/0000-0003-0370-3089
Assunto::	Pão sem glúten Índice glicêmico Pão sem glúten - ingredientes
Issue Date:	2021
Publisher:	MDPI
Citation:	ROMÃO, Bernardo et al. Glycemic Index of gluten-free bread and their main ingredients: a systematic review and meta-analysis. Foods, v. 10, n. 3, 506, 2021. DOI: https://doi.org/10.3390/foods10030506. Disponível em: https://www.mdpi.com/2304-8158/10/3/506. Acesso em: 06 ago. 2021.
Abstract:	This study aimed to perform a systematic review and meta-analysis of the glycemic index (GI) of gluten-free bread (GFB) and its main ingredients. The systematic review followed PRISMA guidelines, using seven electronic databases (PubMed, EMBASE, Scopus, Science Direct, Web of Science, gray literature research with Google Scholar, and patents with Google Patent tool), from inception to November 2020. Eighteen studies met the inclusion criteria evaluating 132 GFB samples. Five articles tested GI in vivo, eleven in vitro; and two studies tested both methods. The analysis showed that 60.7% (95% CI: 40.2–78.1%) of the samples presented high glycemic indexes, evidencing a high glycemic profile for GFB. Only 18.2% (95% CI: 11.7–27.2%) of the bread samples presented in the studies were classified as a low GI. Meta-analysis presented moderate/low heterogenicity between studies (I2 = 61% and <1% for both high and low GIs) and reinforced the proportion of high GIs. Lower GIs were found in formulations based on Colocasia esculenta flour or enriched with fiber, yogurt and curd cheese, sourdough, psyllium, hydrocolloids, enzymes, fructans, and resistant starch, highlighting the efficacy of these ingredients to lower GFBs’ GI. GFB tends to present high GI, impacting the development of chronic diseases when consumed.
Licença::	Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
DOI:	https://doi.org/10.3390/foods10030506
Appears in Collections:	Artigos publicados em periódicos e afins

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