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Title: Impact of a chromosome X STR Decaplex in deficiency paternity cases
Authors: Trindade Filho, Aluisio
Ferreira, Samuel
Oliveira, Silviene Fabiana de
Assunto:: Genética forense
Paternidade
Issue Date: 2013
Publisher: Sociedade Brasileira de Genética
Citation: TRINDADE FILHO, Aluisio; FERREIRA, Samuel; OLIVEIRA, Silviene Fabiana de. Impact of a chromosome X STR Decaplex in deficiency paternity cases. Genetics and Molecular Biology, São Paulo, v. 36, n. 4, p. 507-510, 2013. DOI: https://doi.org/10.1590/S1415-47572013000400008. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400008&lng=en&nrm=iso. Acesso em: 04 dez. 2020.
Abstract: Deficiency paternity cases, characterized by the absence of the alleged father, are a challenge for forensic genetics. Here we present four cases with a female child and a deceased alleged father in which the analysis of a set of 21 or 22 autosomal STRs (AS STRs) produced results within a range of doubt when genotyping relatives of the alleged father. Aiming to increase the Paternity Index (PI) and obtain more reliable results, a set of 10 X-linked STR markers, developed by the Spanish and Portuguese Group of the International Society for Forensic Genetics (ISFG), was then added. Statistical analysis substantially shifted the results towards the alleged fatherhood in all four cases, with more dramatic changes when the supposed half-sister and respective mother were the relatives tested.
Licença:: Genetics and Molecular Biology - Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (CC BY NC 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400008&lng=en&nrm=iso. Acesso em: 04 dez. 2020.
DOI: https://dx.doi.org/10.1590/S1415-47572013000400008
Appears in Collections:Artigos publicados em periódicos e afins

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