Skip navigation
Use este identificador para citar ou linkar para este item: http://repositorio.unb.br/handle/10482/28806
Arquivos associados a este item:
Arquivo TamanhoFormato 
ARTIGO_DoesAcuteAlcohol.pdf413,36 kBAdobe PDFVisualizar/Abrir
Título: Does acute alcohol intoxication interfere with colonic anastomosis wound healing? : a rat model of nondestructive colon trauma
Autor(es): Morais, Pedro Henrique Alves de
Farias, Igor Eduardo Caetano de
Ribeiro, Vinícius Lacerda
Silva, Luiz Eduardo Almeida
Carneiro, Fabiana Pirani
Veiga, Joel Paulo Russomano
Sousa, João Batista de
Assunto: Cicatrização de feridas
Alcoolismo
Etanol
Ratos
Data de publicação: 2013
Editora: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
Referência: MORAIS, Pedro Henrique Alves de et al. Does acute alcohol intoxication interfere with colonic anastomosis wound healing?: a rat model of nondestructive colon trauma. Acta Cirúrgica Brasileira, v. 28, n. 10, p. 703-707, 2013. DOI: https://doi.org/10.1590/S0102-86502013001000003. Disponível em: https://www.scielo.br/j/acb/a/cfvmTgXqffGZDFbYFMgqbLJ/?lang=en#. Acesso em: 10 jul. 2021.
Abstract: PURPOSE: To evaluate the effects of acute alcohol intoxication on healing of colonic anastomosis. METHODS: Thirty-six rats were allocated into two groups. Animals in the alcohol (A) were given 2 mL of ethanol diluted in 0.9% saline solution to a concentration of 40% by gavage immediately before anesthesia, whereas control (C) animals received 2 mL of 0.9% saline solution via the same route. A colonic anastomosis was then performed in all animals. On postoperative days 1, 3, and 7, anastomotic breaking strength was assessed and histopathological examination was performed. Change in body weight and mortality were also evaluated. RESULTS: The median of anastomotic tensile strength on the postoperative day 1 was 0.09 Newtons for group A and 0.13 for group C. (p>0.05). The median of anastomotic tensile strength on the postoperative day 3 was 0.13 Newtons for group A and 0.17 for group C. (p>0.05). The median of anastomotic tensile strength on the postoperative day 7 was 0.30 Newtons for group A and 0.35 for group C. (p>0.05). There was no significant difference between the groups A and C, in the first, third or seventh POD (p>0.05), in any of the analyzed parameters. There were no statistical differences between groups in the weight. Three animals died, all from the group A. CONCLUSION: Acute alcohol intoxication did not interfere with wound healing of colonic anastomoses, although it caused early postoperative mortality.
Unidade Acadêmica: Faculdade de Medicina (FMD)
Licença: Acta Cirúrgica Brasileira - This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY NC). Fonte: https://www.scielo.br/j/acb/a/cfvmTgXqffGZDFbYFMgqbLJ/?lang=en#. Acesso em: 10 jul. 2021.
DOI: https://dx.doi.org/10.1590/S0102-86502013001000003
Aparece nas coleções:Artigos publicados em periódicos e afins

Mostrar registro completo do item Visualizar estatísticas



Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.