Título:	Proteases of haematophagous arthropod vectors are involved in blood-feeding, yolk formation and immunity : a review
Autor(es):	Santiago, Paula Beatriz Araújo, Carla Nunes de Motta, Flávia Nader Praça, Yanna Reis Charneau, Sébastien Bastos, Izabela Marques Dourado Santana, Jaime Martins de
Assunto:	Enzimas proteolíticas Doenças infecciosas Carrapato Mosquito Triatomíneos Vetores - controle
Data de publicação:	13-Fev-2017
Editora:	BioMed Central
Referência:	SANTIAGO, Paula Beatriz et al. Proteases of haematophagous arthropod vectors are involved in blood-feeding, yolk formation and immunity: a review. Parasites & Vectors, v. 10, Article 79, 13 fev. 2017. Disponível em: <https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-017-2005-z>. Acesso em: 13 jun. 2017. doi: https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-017-2005-z.
Abstract:	Ticks, triatomines, mosquitoes and sand flies comprise a large number of haematophagous arthropods considered vectors of human infectious diseases. While consuming blood to obtain the nutrients necessary to carry on life functions, these insects can transmit pathogenic microorganisms to the vertebrate host. Among the molecules related to the blood-feeding habit, proteases play an essential role. In this review, we provide a panorama of proteases from arthropod vectors involved in haematophagy, in digestion, in egg development and in immunity. As these molecules act in central biological processes, proteases from haematophagous vectors of infectious diseases may influence vector competence to transmit pathogens to their prey, and thus could be valuable targets for vectorial control.
Licença:	© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
DOI:	https://dx.doi.org/10.1186/s13071-017-2005-z
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