Skip navigation
Please use this identifier to cite or link to this item: http://repositorio.unb.br/handle/10482/12941
Files in This Item:
File Description SizeFormat 
ARTIGO_UseHerbalMedicine.pdf74,51 kBAdobe PDFView/Open
Title: The use of herbal medicine in Alzheimer’s disease : a systematic review
Authors: Santos Neto, Leopoldo Luiz dos
Toledo, Maria Alice de Vilhena
Souza, Patrícia Medeiros de
Souza, Gustavo Almeida de
Assunto:: Alzheimer, Doença de
Idosos - doenças
Ervas - uso terapêutico
Tratamento alternativo
Issue Date: Oct-2006
Publisher: Hindawi Publishing Corporation
Citation: SANTOS NETO, Leopoldo et al. The use of herbal medicine in Alzheimer’s disease: a systematic review. Evidence-Based Complementary and Alternative Medicine, v. 3, n. 4, out. 2006. Disponível em: <http://www.hindawi.com/journals/ecam/2006/429564/abs/>. Acesso em: 26 abr. 2013. DOI: 10.1093/ecam/nel071.
Abstract: The treatments of choice in Alzheimer's disease (AD) are cholinesterase inhibitors and NMDA-receptor antagonists, although doubts remain about the therapeutic effectiveness of these drugs. Herbal medicine products have been used in the treatment of Behavioral and Psychological Symptoms of Dementia (BPSD) but with various responses. The objective of this article was to review evidences from controlled studies in order to determine whether herbs can be useful in the treatment of cognitive disorders in the elderly. Randomized controlled studies assessing AD in individuals older than 65 years were identified through searches of MEDLINE, LILACS, Cochrane Library, dissertation Abstract (USA), ADEAR (Alzheimer's Disease Clinical Trials Database), National Research Register, Current Controlled trials, Centerwatch Trials Database and PsychINFO Journal Articles. The search combined the terms Alzheimer disease, dementia, cognition disorders, Herbal, Phytotherapy. The crossover results were evaluated by the Jadad's measurement scale. The systematic review identified two herbs and herbal formulations with therapeutic effects for the treatment of AD: Melissa officinalis, Salvia officinalis and Yi-Gan San and BDW (Ba Wei Di Huang Wan). Ginkgo biloba was identified in a meta-analysis study. All five herbs are useful for cognitive impairment of AD. M. officinalis and Yi-Gan San are also useful in agitation, for they have sedative effects. These herbs and formulations have demonstrated good therapeutic effectiveness but these results need to be compared with those of traditional drugs. Further large multicenter studies should be conducted in order to test the cost-effectiveness of these herbs for AD and the impact in the control of cognitive deterioration.
Licença:: Copyright © 2006 Leopoldo Luiz dos Santos-Neto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: http://www.hindawi.com/journals/ecam/2006/429564/abs/. Acesso em: 26 abr. 2013.
DOI: https://dx.doi.org/10.1093/ecam/nel071
Appears in Collections:Artigos publicados em periódicos e afins

Show full item record " class="statisticsLink btn btn-primary" href="/jspui/handle/10482/12941/statistics">



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.