| Campo DC | Valor | Lengua/Idioma |
|---|
| dc.contributor.author | Fraiha, Rafael Ovando | pt_BR |
| dc.contributor.author | Pereira, Ana Paula Ramos | pt_BR |
| dc.contributor.author | Brito, Eliana da Costa Alvarenga | pt_BR |
| dc.contributor.author | Borges, Clayton Luiz | pt_BR |
| dc.contributor.author | Parente, Ana Flávia Alves | pt_BR |
| dc.contributor.author | Perdomo, Renata Trentin | pt_BR |
| dc.contributor.author | Macedo, Maria Ligia Rodrigues | pt_BR |
| dc.contributor.author | Weber, Simone Schneider | pt_BR |
| dc.date.accessioned | 2020-01-24T10:29:59Z | - |
| dc.date.available | 2020-01-24T10:29:59Z | - |
| dc.date.issued | 2019 | pt_BR |
| dc.identifier.citation | FRAIHA, Rafael Ovando et al. Stress conditions in the host induce persister cells and influence biofilm formation by Staphylococcus epidermidis RP62A. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 52, e20180001, 2019. DOI: https://doi.org/10.1590/0037-8682-0001-2018. Disponível em: http://scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100608. Acesso em: 23 jan. 2020. | pt_BR |
| dc.identifier.uri | https://repositorio.unb.br/handle/10482/36247 | - |
| dc.language.iso | en | pt_BR |
| dc.publisher | Sociedade Brasileira de Medicina Tropical - SBMT | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.title | Stress conditions in the host induce persister cells and influence biofilm formation by Staphylococcus epidermidis RP62A | pt_BR |
| dc.type | Artigo | pt_BR |
| dc.subject.keyword | Persistência | pt_BR |
| dc.subject.keyword | Inanição | pt_BR |
| dc.subject.keyword | Virulência (Microbiologia) | pt_BR |
| dc.rights.license | OPEN ACCESS - https://creativecommons.org/licenses/by/4.0/ (CC BY) | - |
| dc.identifier.doi | https://doi.org/10.1590/0037-8682-0001-2018 | pt_BR |
| dc.description.abstract1 | INTRODUCTION: Studies have demonstrated that pathogens react to the harsh conditions in human tissues by inducing mechanisms that promote survival. METHODS: Persistence and biofilm-forming ability were evaluated during stress conditions that mimic those in the host. RESULTS: Carbon-source availability had a positive effect on Staphylococcus epidermidis RP62A adhesion during hypoxia, accompanied by a decrease in pH. In contrast, iron limitation led to decreased surface-adherent biomass, accompanied by an increase medium acidification and lactate levels. Interestingly, iron starvation and hypoxia induced persister cells in planktonic culture. CONCLUSIONS: These findings highlight the role of host stress in the virulence of S. epidermidis. | - |
| dc.identifier.orcid | http://orcid.org/0000-0002-4181-142X | - |
| Aparece en las colecciones: | Artigos publicados em periódicos e afins
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