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dc.contributor.authorPinto, Francisco das Chagas L.-
dc.contributor.authorUchoa, Daniel Esdras de Andrade-
dc.contributor.authorSilveira, Edilberto Rocha-
dc.contributor.authorPessoa, Otília Deusdênia Loiola-
dc.contributor.authorBraz-Filho, Raimundo-
dc.contributor.authorSilva, Fernanda Melo e-
dc.contributor.authorTheodoro, Phellipe Norato Estrela Terra-
dc.contributor.authorEspindola, Laila Salmen-
dc.date.accessioned2013-06-12T21:41:44Z-
dc.date.available2013-06-12T21:41:44Z-
dc.date.issued2011-
dc.identifier.citationPINTO, Francisco das Chagas L. et al. Glicoalcaloides antifúngicos, flavonoides e outros constituintes químicos de Solanum asperum. Química Nova, São Paulo, v. 34, n. 2, 2011. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000200021&lng=pt&nrm=iso&tlng=pt>. Acesso em: 6 jun. 2013.en
dc.identifier.urihttp://repositorio.unb.br/handle/10482/13310-
dc.language.isoPortuguêsen
dc.publisherSociedade Brasileira de Químicaen
dc.rightsAcesso Abertoen
dc.titleGlicoalcaloides antifúngicos, flavonoides e outros constituintes químicos de Solanum asperumen
dc.title.alternativeAntifungal glycoalkaloids, flavonoids and other chemical constituents of Solanum asperum Rich (Solanaceae)en
dc.typeArtigoen
dc.subject.keywordSolanum asperumen
dc.subject.keywordAntimicóticosen
dc.subject.keywordPlantas - compostos bioativosen
dc.rights.licenseQuímica Nova - Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)). Fonte: http://www.scielo.br/scielo.php?script=sci_serial&pid=0100-4042&lng=pt&nrm=iso. Acesso em: 6 jun. 2013.en
dc.identifier.doihttp://dx.doi.org/10.1590/S0100-40422011000200021en
dc.description.abstract1Two glycoalkaloids: solamargine and solasonine; three flavonoids: tiliroside, 7-O-α-L-ramnopyranosyl-kaempferol and 3-O-[ß-D-glucopyranosyl-(1→6)-α-L-ramnopyranosyl]-7- O-α-L-ramnopyranosyl-kaempferol, in addition to the tripeptide Leu-Ile-Val, the aminoacid proline and the eicosanoic acid were isolated from Solanum asperum (Solanaceae). The structures of all compounds were determined by interpretation of their spectra (IR, MS, 1H and 13C NMR) and comparison with the literature data. All compounds, except the glycoalkaloids, are being reported for the first time for S. asperum. Solasonine showed strong activity (MIC < 0.24 μg/mL) against four filamentous fungi species of the genera Microsporum and Trichophyton.-
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