| Campo DC | Valor | Idioma |
|---|
| dc.contributor.author | Mendes, Marcela Moraes | - |
| dc.contributor.author | Araújo, Maísa Mirande | - |
| dc.contributor.author | Botelho, Patrícia Borges | - |
| dc.contributor.author | Carvalho, Kênia Mara Baiocchi de | - |
| dc.date.accessioned | 2024-10-23T18:36:18Z | - |
| dc.date.available | 2024-10-23T18:36:18Z | - |
| dc.date.issued | 2024 | - |
| dc.identifier.citation | MENDES, Marcela Moraes et al. Seasonal and sex-related variation in vitamin D status and its association with other biochemical markers in young individuals: a cross-sectional study. Plos One, [S. l.], v. 19, n. 3, e0298862, 2024. DOI: https://doi.org/10.1371/journal.pone.0298862. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0298862. Acesso em: 23 out. 2024. | pt_BR |
| dc.identifier.uri | http://repositorio.unb.br/handle/10482/50682 | - |
| dc.language.iso | eng | pt_BR |
| dc.publisher | Plos One | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.title | Seasonal and sex-related variation in vitamin D status and its association with other biochemical markers in young individuals : a cross-sectional study | pt_BR |
| dc.type | Artigo | pt_BR |
| dc.subject.keyword | Vitamina D | pt_BR |
| dc.subject.keyword | Marcadores bioquímicos | pt_BR |
| dc.subject.keyword | Jovens | pt_BR |
| dc.rights.license | © 2024 Mendes et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | pt_BR |
| dc.identifier.doi | https://doi.org/10.1371/journal.pone.0298862 | pt_BR |
| dc.description.abstract1 | Background
While several studies have investigated the association between vitamin D deficiency and
biochemical parameters, the results are still inconsistent and mostly overlook seasonal variations. This study explored the relationships between 25-hydroxy-vitamin D (25(OH)D) concentrations, biochemical markers, and seasonal variation among young males and females.
Methods
A cross-sectional study was conducted among 203 individuals aged 18–24 years of both
sexes residing in Brasilia, Brazil (latitude: 15˚S). Sociodemographic variables, season of
blood collection, and serum levels of 25(OH)D, total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, glycated hemoglobin (HbA1c), glucose, insulin, hs-CRP, parathyroid
hormone, ionized calcium, and alkaline phosphatase were included. Descriptive statistics
and differences among groups, correlations, and linear regression tests were performed.
Results
The mean age of the participants was 21.17±1.7 years, and the mean serum 25(OH)D level
was 25.76±7.0 ng/mL. Of the participants, 50.7% had vitamin D insufficiency (20 to 29.9 ng/
mL), and 23.2% were vitamin D deficient (≥ 20 ng/mL). Vitamin D deficiency was higher in
the spring (53.2%) and among females (29.5%). In young men with vitamin D insufficiency/
deficiency (≥29.9 ng/mL) (n = 49), 25(OH)D levels were inversely correlated with HOMA-β
(r = -0.234, p = 0.032) and triglyceride (r = -0.415, p = 0.003) levels. However, there were no
significant correlations between 25(OH)D concentrations and biochemical markers among
women with insufficient and deficient vitamin D levels. Conclusion
This study found a high prevalence of vitamin D insufficiency/deficiency among young individuals living in Brası´lia, Brazil, particularly women and during the spring season. Our findings suggest that lower 25(OH)D levels (≥29.9 ng/mL) may be associated with insulin
resistance and an increased risk of cardiovascular disease in young men studied. However,
further studies with larger representative samples are needed to explore the mechanisms
underlying the association between vitamin D and biochemical parameters. | pt_BR |
| dc.identifier.orcid | https://orcid.org/0000-0001-8232-7653 | pt_BR |
| dc.contributor.affiliation | University of Brasilia, Graduate Program in Human Nutrition, Department of Nutrition | pt_BR |
| dc.contributor.affiliation | Federal University of Goias, Faculty of Nutrition, Postgraduate Program | pt_BR |
| dc.contributor.affiliation | University of Brasilia, Graduate Program in Human Nutrition, Department of Nutrition | pt_BR |
| dc.contributor.affiliation | University of Brasilia, Graduate Program in Human Nutrition, Department of Nutrition | pt_BR |
| dc.description.unidade | Faculdade de Ciências da Saúde (FS) | pt_BR |
| dc.description.unidade | Departamento de Nutrição (FS NUT) | pt_BR |
| dc.description.ppg | Programa de Pós-Graduação em Nutrição Humana | pt_BR |
| Aparece nas coleções: | Artigos publicados em periódicos e afins
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