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dc.contributor.authorIllanes Tormena, Renata Pascoal-
dc.contributor.authorRosa, Eliane Vieira-
dc.contributor.authorMota, Bruna de Fatima Oliveira-
dc.contributor.authorChaker, Juliano Alexandre-
dc.contributor.authorFagg, Christopher William-
dc.contributor.authorFreire, Daniel Oliveira-
dc.contributor.authorMartins, Paula Melo-
dc.contributor.authorSilva, Izabel Cristina Rodrigues da-
dc.contributor.authorSousa, Marcelo Henrique-
dc.date.accessioned2023-11-27T13:46:52Z-
dc.date.available2023-11-27T13:46:52Z-
dc.date.issued2020-06-21-
dc.identifier.citationILLANES TORMENA, Renata Pascoal et al. Evaluation of the antimicrobial activity of silver nanoparticles obtained by microwave-assisted green synthesis using Handroanthus impetiginosus (Mart. ex DC.) Mattos underbark extract. RSC Advances, [S. l.], v. 10, n. 35, 20676-20681, 2020. DOI: 10.1039/d0ra03240a. Disponível em: https://pubs.rsc.org/en/content/articlelanding/2020/RA/D0RA03240A. Acesso em: 28 nov. 2023.pt_BR
dc.identifier.urihttp://repositorio2.unb.br/jspui/handle/10482/46911-
dc.language.isoengpt_BR
dc.publisherThe Royal Society of Chemistrypt_BR
dc.rightsAcesso Abertopt_BR
dc.titleEvaluation of the antimicrobial activity of silver nanoparticles obtained by microwave-assisted green synthesis using Handroanthus impetiginosus (Mart. ex DC.) Mattos underbark extractpt_BR
dc.typeArtigopt_BR
dc.subject.keywordAtividade antimicrobianapt_BR
dc.subject.keywordNanopartículas de pratapt_BR
dc.subject.keywordIpê roxopt_BR
dc.rights.license(CC BY-NC). This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licencept_BR
dc.identifier.doihttps://doi.org/10.1039/D0RA03240Apt_BR
dc.description.abstract1We describe here a green method for the preparation of silver nanoparticles (AgNPs), by a microwave assisted synthesis route using Handroanthus impetiginosus underbark extract, with antibacterial activity. After optimizing the synthesis parameters with a Box–Benhken designed experiment, samples were characterized by powder XRD, TEM, UV-Vis spectroscopy, FTIR and zetametry. Using the overall optimized conditions of synthesis – time of reaction 15 min at 200 C and plant extract/AgNO3 volume ratio equal to 10% – highly crystalline 13.4 nm-sized spherical AgNPs in a well-dispersed colloidal state were obtained. It was also proved that the plant extract compounds act as reductant and capping agents during synthesis to functionalize AgNPs, resulting in a negatively charged surface with high values of zeta potential in a wide range of pH, from acidic to alkaline media. Biological activity tests against Staphylococcus aureus and Escherichia coli and cell viability experiments showed that synthesized AgNPs were not toxic to HaCaT mammalian cells and presented a high efficiency against Gram-positive bacteria (S. aureus). This was associated with the synergistic combination of AgNP silver cores with the capping layer containing natural compounds with antimicrobial properties and considered an alternative to the AgNPs commonly obtained from conventional routes that present antibacterial effectiveness preferentially against Gram-negative strains.pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3248-1286pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-2144-0959pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6072-7832pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-1210-8329pt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Ceilandia, Green Nanotechnology Grouppt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Ceilandia, Green Nanotechnology Grouppt_BR
dc.contributor.affiliationFederal Institute of Education, Science and Technology Goiano, Ceres, GOpt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Ceilandia, Department of Pharmacypt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Ceilandia, Green Nanotechnology Grouppt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Ceilandia, Graduate Program in Health Sciences and Technologiespt_BR
dc.contributor.affiliationLS Educational, Microbiology Laboratory, Brasilia, Brazilpt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Ceilandia, Department of Pharmacypt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Ceilandia, Graduate Program in Health Sciences and Technologiespt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Ceilandia, Green Nanotechnology Grouppt_BR
dc.description.unidadeFaculdade UnB Ceilândia (FCE)pt_BR
dc.description.unidadeCurso de Farmácia (FCE-FAR)pt_BR
dc.description.ppgPrograma de Pós-Graduação em Ciências e Tecnologias em Saúdept_BR
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