Título:	Evolution of research funding for neglected tropical diseases in Brazil, 2004–2020
Autor(es):	Melo, Gabriela Bardelini Tavares Tuesta, Antonia de Jesus Angulo Silva, Everton Nunes da Santos, Thaís da Silva Uchimura, Liza Yurie Teruya Obara, Marcos Takashi
ORCID:	https://orcid.org/0000-0002-6758-0834
Afiliação do autor:	University of Brasilia, Faculty of Ceilândia, Graduate Program in Health Sciences and Technologies Ministry of Health, Department of Science and Technology, Federal District, Brasilia, Brazil University of Brasilia, Faculty of Ceilândia, Graduate Program in Health Sciences and Technologies University of Brasilia, Faculty of Ceilândia, Graduate Program in Health Sciences and Technologies University of Brasilia, Faculty of Ceilândia, Graduate Program in Health Sciences and Technologies Hospital do Coração, São Paulo State University of Brasilia, Faculty of Ceilândia, Graduate Program in Health Sciences and Technologies
Assunto:	Doenças tropicais Pesquisa em saúde - financiamento Política de saúde
Data de publicação:	Mar-2023
Editora:	Plos
Referência:	MELO, Gabriela Bardelini Tavares et al. Evolution of research funding for neglected tropical diseases in Brazil, 2004–2020. PLOS Neglected Tropical Diseases, v. 17, n. 3, e0011134, 2023. DOI: https://doi.org/10.1371/journal.pntd.0011134. Disponível em: https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0011134.
Abstract:	Neglected tropical diseases are a global public health problem. Although Brazil is largely responsible for their occurrence in Latin America, research funding on the subject does not meet the population’s health needs. The present study analyzed the evolution of research funding for neglected tropical diseases by the Ministry of Health and its partners in Brazil, from 2004 to 2020. This is a retrospective study of data from investigations registered on Health Research (Pesquisa Saúde in Portuguese), a public repository for research funded by the Ministry of Health’s Department of Science and Technology. The temporal trend of funding and the influence of federal government changes on funding were analyzed using Prais-Winster generalized linear regression. From 2004 to 2020, 1,158 studies were financed (purchasing power parity (PPP$) 230.9 million), with most funding aimed at biomedical research (81.6%) and topics involving dengue, leishmaniasis and tuberculosis (60.2%). Funding was stationary (annual percent change of -5.7%; 95%CI -54.0 to 45.0) and influenced by changes to the federal government. Research funding was lacking for chikungunya, Chagas disease, schistosomiasis, malaria and taeniasis/cysticercosis, diseases with a high prevalence, burden or mortality rates in Brazil. Although the Ministry of Health had several budgetary partners, it was the main funder, with 69.8% of investments. The study revealed that research funding for neglected tropical diseases has stagnated over the years and that diseases with a high prevalence, burden and mortality rate receive little funding. These findings demonstrate the need to strengthen the health research system by providing sustainable funding for research on neglected tropical diseases that is consistent with the population’s health needs.
Unidade Acadêmica:	Faculdade UnB Ceilândia (FCE)
Programa de pós-graduação:	Programa de Pós-Graduação em Ciências e Tecnologias em Saúde
Licença:	Copyright: © 2023 Melo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
DOI:	https://doi.org/10.1371/journal.pntd.0011134
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