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dc.contributor.authorRios, Salete da Silva-
dc.contributor.authorChen, Ana Carolina Rios-
dc.contributor.authorChen, Juliana Rios-
dc.contributor.authorResende, Ceres Nunes de-
dc.contributor.authorAraujo Júnior, Edward-
dc.date.accessioned2023-07-10T15:00:46Z-
dc.date.available2023-07-10T15:00:46Z-
dc.date.issued2022-
dc.identifier.citationRIOS,Salete S. et al. Coronavirus 2019 disease: are corticosteroids the key treatment?: a retrospective case-control study in Brazil. Annals of Medicine and Surgery, [S.l.], v. 82, 104746, 2022. DOI: https://doi.org/10.1016/j.amsu.2022.104746. Disponível em: https://www.sciencedirect.com/science/article/pii/S2049080122015060. Acesso em 08 jul. 2023.pt_BR
dc.identifier.urihttp://repositorio2.unb.br/jspui/handle/10482/46045-
dc.description.abstractBackground: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the putative cause of coronavirus disease 2019 (COVID-19), a serious disease that has severely impacted the world. Although vaccines have been developed, it will take time to inoculate the global population. Current guidelines have focused on the treatment of severe cases in hospital settings; however, a void has been created regarding appropriate measures for those in the initial stage of COVID-19 and those experiencing moderate disease severity progressing to desaturation. We assessed clinical outcomes in patients with COVID-19 with pneumonia at initial presentation treated with corticosteroids. Methods: Data of 177 consecutive high-risk patients with COVID-19, monitored by telemedicine, were collected and analyzed. Of those, 68 patients were in the initial inflammatory phase of the disease without desaturation and received corticosteroids. The outcomes were evaluated after a follow up of 14 days. Four patients were immediately referred to the hospital because they had explicit desaturation at presentation. Results: After 14 days, all patients in the inflammatory phase at presentation who were treated with corticosteroids before desaturation were alive and without complications. However, of the four patients with desaturation, one died at the hospital. Conclusion: In this study, the use of corticosteroids during the initial pulmonary phase of COVID-19 before desaturation, in addition to daily monitoring of patients, prevented disease progression, decreased the risk of complications and incidence of hospitalization and death. However, additional studies with larger number of patients are needed to confirm these findings.pt_BR
dc.language.isoengpt_BR
dc.publisherElsevier Ltd on behalf of IJS Publishing Group Ltd.pt_BR
dc.rightsAcesso Abertopt_BR
dc.titleCoronavirus 2019 disease : are corticosteroids the key treatment? : a retrospective case-control study in Brazilpt_BR
dc.typeArtigopt_BR
dc.subject.keywordCovid-19pt_BR
dc.subject.keywordCorticóidept_BR
dc.rights.license© 2022 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.amsu.2022.104746pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-2798-3564pt_BR
dc.contributor.affiliationUniversity of Brasília, School of Medicinept_BR
dc.contributor.affiliationUniversity of Brasília, School of Medicinept_BR
dc.contributor.affiliationUniversity of Brasília, School of Medicinept_BR
dc.contributor.affiliationUniversity of Brasília, School of Medicinept_BR
dc.contributor.affiliationFederal University of São Paulo, Department of Obstetrics Paulista School of Medicinept_BR
dc.contributor.affiliationMunicipal Universidade of São Caetano Do Sul, Medical Course, Bela Vista Campuspt_BR
dc.description.unidadeFaculdade de Medicina (FMD)pt_BR
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