Título:	An overview on immunogenic cell death in cancer biology and therapy
Autor(es):	Rodrigues, Mosar Corrêa Morais, José Athayde Vasconcelos Ganassin, Rayane Oliveira, Giulia Rosa Tavares Costa, Fabiana Chagas Morais, Amanda Alencar Cabral Silveira, Ariane Pandolfo Silva, Victor Carlos Mello Longo, João Paulo Figueiró Muehlmann, Luis Alexandre
E-mail do autor:	mailto:mosarcr@gmail.com mailto:joseavmorais@gmail.com mailto:rayaneganassin@hotmail.com mailto:giulia_rosa12@hotmail.com mailto:fchagas16@gmail.com mailto:amandaalencarcabral@gmail.com mailto:pandolfo.ariane@gmail.com mailto:victor@spctm.com mailto:jplongo82@gmail.com mailto:luisalex@unb.br
ORCID:	https://orcid.org/0000-0003-3067-4842 https://orcid.org/0000-0002-6974-0889 https://orcid.org/0000-0002-5154-7263
Assunto:	Morte celular imunogênica Câncer - tratamento Sistema imunológico
Data de publicação:	27-Jul-2022
Editora:	MDPI
Referência:	RODRIGUES, Mosar Corrêa et al. An overview on immunogenic cell death in cancer biology and therapy. Pharmaceutics, Basel, v. 14, n. 8, art. 1564, jul. 2022. DOI 10.3390/pharmaceutics14081564. Disponível em: https://www.mdpi.com/1999-4923/14/8/1564. Acesso em: 23 set. 2022.
Abstract:	Immunogenic cell death (ICD) is a modality of regulated cell death that is sufficient to promote an adaptive immune response against antigens of the dying cell in an immunocompetent host. An important characteristic of ICD is the release and exposure of damage-associated molecular patterns, which are potent endogenous immune adjuvants. As the induction of ICD can be achieved with conventional cytotoxic agents, it represents a potential approach for the immunotherapy of cancer. Here, different aspects of ICD in cancer biology and treatment are reviewed.
Licença:	Pharmaceutics - Articles published in Sustainability will be Open-Access articles distributed under the terms and conditions of the Creative Commons Attribution License (CC BY). The copyright is retained by the author(s). MDPI will insert the following note at the end of the published text: © 2022 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). Fonte: https://www.mdpi.com/journal/pharmaceutics/about. Acesso em: 23 set. 2022.
DOI:	https://doi.org/10.3390/pharmaceutics14081564
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