| Campo DC | Valor | Idioma |
|---|
| dc.contributor.author | Zidorio, Ana Paula | - |
| dc.contributor.author | Togo, Camille | - |
| dc.contributor.author | Jones, Rosie | - |
| dc.contributor.author | Dutra, Eliane Said | - |
| dc.contributor.author | Carvalho, Kênia Mara Baiocchi de | - |
| dc.date.accessioned | 2022-04-26T15:02:28Z | - |
| dc.date.available | 2022-04-26T15:02:28Z | - |
| dc.date.issued | 2019-06-03 | - |
| dc.identifier.citation | ZIDORIO, Ana Paula et al. Resting energy expenditure and protein balance in people with Epidermolysis Bullosa. Nutrients, v. 11, n. 6, 1257, 2019. DOI: https://doi.org/10.3390/nu11061257. Disponível em: https://www.mdpi.com/2072-6643/11/6/1257. Acesso em: | pt_BR |
| dc.identifier.uri | https://repositorio.unb.br/handle/10482/43540 | - |
| dc.language.iso | Inglês | pt_BR |
| dc.publisher | MDPI | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.title | Resting energy expenditure and protein balance in people with Epidermolysis Bullosa | pt_BR |
| dc.type | Artigo | pt_BR |
| dc.subject.keyword | Epidermólise bullosa | pt_BR |
| dc.subject.keyword | Nutrição | pt_BR |
| dc.subject.keyword | Gasto energético | pt_BR |
| dc.subject.keyword | Balanço de azoto | pt_BR |
| dc.subject.keyword | Catabolismo | pt_BR |
| dc.rights.license | 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | pt_BR |
| dc.identifier.doi | https://doi.org/10.3390/nu11061257 | pt_BR |
| dc.description.abstract1 | Epidermolysis bullosa (EB) is a group of conditions characterized by severe fragility of the skin that causes recurring blistering. The recessive dystrophic subtype of EB (RDEB) has a strong impact on the nutritional status. We evaluated the resting energy expenditure (REE) and presence of protein catabolism in patients with RDEB. REE was assessed in 10 subjects (7 females; age range 4–33 years) by indirect calorimetry and using a predictive equation. Nitrogen balance was calculated by protein intake and 24 h urinary urea excretion estimations. An assessment of body surface area (BSA) with infected and non-infected skin lesions was applied to the nitrogen balance burn equation that was adapted to EB. The REE values predicted by the equation were consistently lower than the ones measured, except for two subjects. All subjects recorded high protein and energy intake, with
protein intake being higher than 4 g protein/kg/day for five subjects. Even so, protein catabolism was observed in six subjects, three of whom had infected wounds. This study raises the hypothesis that the clinical and nutritional risks of people with RDEB are associated with an increased REE and negative nitrogen balance, which reinforces the importance of nutritional support. | pt_BR |
| dc.identifier.orcid | https://orcid.org/ 0000-0003-2799-1038 | pt_BR |
| Aparece nas coleções: | Artigos publicados em periódicos e afins
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