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dc.contributor.authorKurizky, Patricia Shu-
dc.contributor.authorMarianelli, Fernanda Ferraço-
dc.contributor.authorCesetti, Mariana Vicente-
dc.contributor.authorDamiani, Giovanni-
dc.contributor.authorSampaio, Raimunda Nonata Ribeiro-
dc.contributor.authorGonçalves, Lais Mitsue Tanaka-
dc.contributor.authorSousa, Carlos Augusto Felipe de-
dc.contributor.authorMartins, Sofia Sales-
dc.contributor.authorVernal, Sebastian-
dc.contributor.authorMota, Licia Maria Henrique da-
dc.contributor.authorGomes, Ciro Martins-
dc.date.accessioned2021-04-08T17:22:16Z-
dc.date.available2021-04-08T17:22:16Z-
dc.date.issued2020-
dc.identifier.citationKURIZKY, Patrícia Shu et al. A comprehensive systematic review of leishmaniasis in patients undergoing drug-induced immunosuppression for the treatment of dermatological, rheumatological and gastroenterological diseases. Revista do Instituto de Medicina Tropical de São Paulo, São Paulo, v. 62, e28, 2020. DOI: https://doi.org/10.1590/s1678-9946202062028. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652020000100217&lng=en&nrm=iso. Acesso em: 05 abr. 2021.pt_BR
dc.identifier.urihttps://repositorio.unb.br/handle/10482/40462-
dc.language.isoInglêspt_BR
dc.publisherInstituto de Medicina Tropicalpt_BR
dc.rightsAcesso Abertopt_BR
dc.titleA comprehensive systematic review of leishmaniasis in patients undergoing drug-induced immunosuppression for the treatment of dermatological, rheumatological and gastroenterological diseasespt_BR
dc.typeArtigopt_BR
dc.subject.keywordImunossupressãopt_BR
dc.subject.keywordLeishmaniosept_BR
dc.subject.keywordRevisão sistemáticapt_BR
dc.subject.keywordTratamentopt_BR
dc.rights.license(CC BY NC) - This is an open-access article distributed under the terms of the Creative Commons Attribution License.pt_BR
dc.identifier.doihttps://doi.org/10.1590/s1678-9946202062028pt_BR
dc.description.abstract1Immunosuppression is an important risk factor for leishmaniasis. We assessed the clinical profile, geographic distribution and prevalence of leishmaniasis in patients undergoing immunosuppressive therapy for dermatological, rheumatological or gastroenterological autoimmune diseases. We identified relevant studies in PubMed, EMBASE, Scopus, Web of Science and LILACS on July 3rd, 2018. We included articles that reported at least one case of leishmaniasis in patients undergoing immunosuppressive treatment for dermatological, rheumatological or gastroenterological diseases. Our protocol was registered in PROSPERO (CRD42018103050). We assessed the quality of the included studies with the Joanna Briggs Institute Critical Appraisal Tool. After the removal of duplicates, 5,431 articles were collected and screened. We included 138 articles; the prevalence of leishmaniasis in six methodologically similar studies varied from three to 1,282 cases per 100,000 patients using anti-TNFα drugs, but the results were significantly heterogeneous . Leishmaniasis in patients treated with immunosuppressive drugs is a health problem mostly reported in European countries bordering the Mediterranean Sea; sporadic activities, such as travelling, seem not to be associated with a significant risk of leishmaniasis, although effective control measures must always be observed.pt_BR
dc.identifier.orcidhttp://orcid.org/0000-0002-3069-6884pt_BR
dc.description.unidadeFaculdade de Medicina (FMD)-
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