Título:	D-loop haplotype diversity in brazilian horse breeds
Autor(es):	Ianella, Patrícia Albuquerque, Maria do Socorro Maués Paiva, Samuel Rezende Egito, Andréa Alves do Almeida, Leonardo Daniel Sereno, Fabiana T. P. S. Carvalho, Luiz Felipe Ramos Mariante, Arthur da Silva Pimentel, Concepta Margaret McManus
Assunto:	DNA mitocondrial Cavalo - genética
Data de publicação:	Set-2017
Editora:	Sociedade Brasileira de Genética
Referência:	IANELLA, Patrícia et al. D-loop haplotype diversity in brazilian horse breeds. Genetics and Molecular Biology, Ribeirão Preto, v. 40, n. 3, p. 604-609, jul./set. 2017. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000400604&lng=en&nrm=iso>. Acesso em: 18 jan. 2018. Epub Aug 31, 2017. doi: http://dx.doi.org/10.1590/1678-4685-gmb-2016-0166.
Abstract:	The first horses were brought to Brazil by the colonizers after 1534. Over the centuries, these animals evolved and adapted to local environmental conditions usually unsuitable for exotic breeds, thereby originating locally adapted Brazilian breeds. The present work represents the first description of maternal genetic diversity in these horse breeds based on D-loop sequences. A D-Loop HSV-I fragment of 252 bp, from 141 horses belonging to ten Brazilian breeds / genetic groups (locally adapted and specialized breeds) were analysed. Thirty-five different haplotypes belonging to 18 haplogroups were identified with 33 polymorphic sites. Haplotype diversity (varying from 0.20 to 0.96) and nucleotide diversity (varying from 0.0039 to 0.0239) was lower for locally adapted than for specialized breeds, with the same pattern observed for FST values. Haplogroups identified in Brazilian breeds are in agreement with previous findings in South American samples. The low variability observed mainly in locally adapted breeds, indicates that, to ensure conservation of these breeds, careful reproductive management is needed. Additional genetic characterization studies are required to support accurate decision-making.
Unidade Acadêmica:	Faculdade de Agronomia e Medicina Veterinária (FAV)
Licença:	Genetics and Molecular Biology - This is an open-access article distributed under the terms of the Creative Commons Attribution License (type CC-BY), which permits unrestricted use, distribution and reproduction in any medium, provided the original article is properly cited (CC BY 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000400604&lng=en&nrm=iso. Acesso em: 18 jan. 2018.
DOI:	http://dx.doi.org/10.1590/1678-4685-gmb-2016-0166
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