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Use este identificador para citar ou linkar para este item: http://repositorio.unb.br/handle/10482/28698
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dc.contributor.authorMolinet, Félix Javier Leónpt_BR
dc.contributor.authorAmpuero Vela, Julia Soniapt_BR
dc.contributor.authorCosta, Rodrigo Dinizpt_BR
dc.contributor.authorNoronha, Elza Ferreirapt_BR
dc.contributor.authorRomero, Gustavo Adolfo Sierrapt_BR
dc.date.accessioned2017-12-07T05:02:26Z-
dc.date.available2017-12-07T05:02:26Z-
dc.date.issued2013-05pt_BR
dc.identifier.citationMOLINET, Felix Javier Leon et al. Specificity of the rapid rK39 antigen-based immunochromatographic test Kalazar Detect(r) in patients with cutaneous leishmaniasis in Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 108, n. 3, p. 293-296, maio 2013. DOI: https://doi.org/10.1590/S0074-02762013000300006. Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000300293&lng=en&nrm=iso>. Acesso em: 04 dez. 2020.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/28698-
dc.language.isoenpt_BR
dc.publisherInstituto Oswaldo Cruz, Ministério da Saúdept_BR
dc.rightsAcesso Abertopt_BR
dc.titleSpecificity of the rapid rK39 antigen-based immunochromatographic test Kalazar Detect(r) in patients with cutaneous leishmaniasis in Brazilpt_BR
dc.typeArtigopt_BR
dc.subject.keywordLeishmaniose cutâneapt_BR
dc.subject.keywordLeishmania braziliensispt_BR
dc.subject.keywordLeishmania infantumpt_BR
dc.subject.keywordAntígenospt_BR
dc.rights.licenseLICENÇAS E DIREITOS AUTORAIS Memórias do Instituto Oswaldo Cruz - Todo o conteúdo desta revista, exceto indicado de outra forma, está certificado sob uma Licença Creative Commons Attribution 4.0. Isso significa que os autores dão total permissão a qualquer pessoa para compartilhar e adaptar o conteúdo do artigo, desde que os autores originais e a fonte sejam citados. Fonte: https://www.scielo.br/journal/mioc/about/#about. Acesso em: 27 out.2022.-
dc.identifier.doihttps://dx.doi.org/10.1590/S0074-02762013000300006pt_BR
dc.description.abstract1The aim of this study was to evaluate the specificity of a rapid immunochromatographic test that was developed to detect antibodies against the rK39 antigen for the diagnosis of visceral leishmaniasis (VL). This evaluation was performed using sera from patients with a confirmed diagnosis of active cutaneous leishmaniasis. The sera from 272 patients with a confirmed diagnosis of localised cutaneous leishmaniasis (CL) who resided in an area endemic for Leishmania braziliensis in Brazil were obtained before the initiation of antileishmanial treatment. Kalazar Detect(r)(InBios, Seattle, WA) recombinant K39 antigen-based immunochromatographic strips were used according to the manufacturer's instructions. The test results were evaluated independently by two examiners in sequential order. The positive controls for the test included five serum samples from five patients with parasitologically confirmed diagnosis of VL caused by Leishmania infantum in Brazil. Overall, 100% of the samples obtained from patients with CL were negative, confirming the absence of a serological cross-reaction for individuals with cutaneous disease when these patients were evaluated using the rapid test. The lack of a cross-reaction in patients who were infected by parasites of the same genus highlights the specificity of the rK39 antigen for the diagnosis of VL in areas with the sympatric circulation of L. braziliensis and L. infantum.-
dc.description.unidadeFaculdade de Medicina (FMD)-
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