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dc.contributor.authorGrisolia, Cesar Koppe-
dc.contributor.authorRivero, Carla Letícia Gediel-
dc.contributor.authorStarling, Fernando Luis do Rego Monteiro-
dc.contributor.authorSilva, Izabel Cristina Rodrigues da-
dc.contributor.authorBarbosa, Antonio Carneiro-
dc.contributor.authorDórea, José Garrofe-
dc.date.accessioned2013-07-09T17:14:38Z-
dc.date.available2013-07-09T17:14:38Z-
dc.date.issued2009-01-
dc.identifier.citationGRISOLIA, Cesar K. et al. Profile of micronucleus frequencies and DNA damage in different species of fish in a eutrophic tropical lake. Genetics and Molecular Biology, v. 32, n.1, p. 138-143, jan. 2009. Disponível em: <http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1415-47572009000100021&lng=en&nrm=iso&tlng=en>. Acesso em: 5 jul. 2013. DOI: http://dx.doi.org/10.1590/S1415-47572009005000009.en
dc.identifier.urihttp://repositorio.unb.br/handle/10482/13535-
dc.description.abstractLake Paranoá is a tropical reservoir for the City of Brasilia, which became eutrophic due to inadequate sewage treatment associated with intensive population growth. At present, two wastewater treatment plants are capable of processing up to 95% of the domestic sewage, thereby successfully reducing eutrophization. We evaluated both genotoxic and cytotoxic parameters in several fish species (Geophagus brasiliensis, Cichla temensis, Hoplias malabaricus, Astyanax bimaculatus lacustres, Oreochromis niloticus, Cyprinus carpio and Steindachnerina insculpita) by using the micronucleus (MN) test, the comet assay and nuclear abnormality assessment in peripheral erythrocytes. The highest frequencies of MN were found in Cichla temensis and Hoplias malabaricus, which were statistically significant when compared to the other species. However, Steindachnerina insculpita (a detritivorous and lake-floor feeder species) showed the highest index of DNA damage in the comet assay, followed by C. temensis (piscivorous). Nuclear abnormalities, such as binucleated, blebbed, lobed and notched cells, were used as evidence of cytotoxicity. Oreochromis niloticus followed by Hoplias malaricus, ominivorous/detritivotous and piscivorous species, respectively, presented the highest frequency of nuclear abnormalities, especially notched cells, while the herbivorous Astyanax bimaculatus lacustres showed the lowest frequency compared to the other species studied. Thus, for biomonitoring aquatic genotoxins under field conditions, the food web should also be considered.en
dc.language.isoInglêsen
dc.publisherSociedade Brasileira de Genéticaen
dc.rightsAcesso Abertoen
dc.titleProfile of micronucleus frequencies and DNA damage in different species of fish in a eutrophic tropical lakeen
dc.typeArtigoen
dc.subject.keywordToxicidadeen
dc.subject.keywordPeixe - alimentoen
dc.subject.keywordLago Paranoá (DF)en
dc.subject.keywordToxicologia genéticaen
dc.rights.licenseGenetics and Molecular Biology - Todos os conteúdos deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons Attribution (Atribuição-Uso Não-Comercial 3.0 Não Adaptada (CC BY-NC 3.0)). Fonte: http://www.scielo.br/scielo.php?script=sci_serial&pid=1415-4757&lng=en&nrm=iso. Acesso em: 5 jul. 2013.en
dc.identifier.doihttp://dx.doi.org/10.1590/S1415-47572009005000009en
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